Impact of exercise training on redox signaling in cardiovascular diseases

被引：50

作者：

Campos, Juliane C. ^{[1
]}

Gomes, Katia M. S. ^{[1
]}

Ferreira, Julio C. B. ^{[1
]}

机构：

[1] Univ Sao Paulo, Inst Ciencias Biomed, Dept Anat, BR-05508000 Sao Paulo, Brazil

来源：

FOOD AND CHEMICAL TOXICOLOGY | 2013年 / 62卷

基金：

巴西圣保罗研究基金会;

关键词：

Free radicals; Cardiac disease; Physical activity; Bioenergetics; Oxidative stress; Oxidative metabolism; NITRIC-OXIDE SYNTHASE; CHRONIC HEART-FAILURE; MYOCARDIAL ISCHEMIA/REPERFUSION INJURY; ISCHEMIA-REPERFUSION INJURY; INTENSITY AEROBIC EXERCISE; OXYGEN SPECIES PRODUCTION; RAT CARDIAC PROTEINS; OXIDATIVE STRESS; SKELETAL-MUSCLE; SYMPATHETIC HYPERACTIVITY;

D O I：

10.1016/j.fct.2013.08.035

中图分类号：

TS2 [食品工业];

学科分类号：

100403 [营养与食品卫生学];

摘要：

Reactive oxygen and nitrogen species regulate a wide array of signaling pathways that governs cardiovascular physiology. However, oxidant stress resulting from disrupted redox signaling has an adverse impact on the pathogenesis and progression of cardiovascular diseases. In this review, we address how redox signaling and oxidant stress affect the pathophysiology of cardiovascular diseases such as ischemia-reperfusion injury, hypertension and heart failure. We also summarize the benefits of exercise training in tackling the hyperactivation of cellular oxidases and mitochondrial dysfunction seen in cardiovascular diseases. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：107 / 119

页数：13

共 191 条

[1]

Impact of regular physical activity on the NAD(P)H oxidase and angiotensin receptor system in patients with coronary artery disease [J].

Adams, V ;

Linke, A ;

Kränkel, N ;

Erbs, S ;

Gielen, S ;

Möbius-Winkler, S ;

Gummert, JF ;

Mohr, FW ;

Schuler, G ;

Hambrecht, R .

CIRCULATION, 2005, 111 (05) :555-562

[2]

AMAYA Y, 1990, J BIOL CHEM, V265, P14170

[3]

[Anonymous], 2011, Global Atlason Cardiovascular Disease Prevention and Control: Published by theWorld Health Organization in Collaboration with the World Heart Federationand the World Stroke Organization

[4]

Peroxisomes Are Oxidative Organelles [J].

Antonenkov, Vasily D. ;

Grunau, Silke ;

Ohlmeier, Steffen ;

Hiltunen, J. Kalervo .

ANTIOXIDANTS & REDOX SIGNALING, 2010, 13 (04) :525-537

[5]

Endurance training attenuates doxorubicin-induced cardiac oxidative damage in mice [J].

Ascensao, A ;

Magalhaes, J ;

Soares, J ;

Ferreira, R ;

Neuparth, M ;

Marques, F ;

Oliveira, J ;

Duarte, J .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2005, 100 (03) :451-460

[6]

Endurance training limits the functional alterations of heart rat mitochondria submitted to in vitro anoxia-reoxygenation [J].

Ascensao, Antonio ;

Magalhaes, Jose ;

Soares, Jose M. C. ;

Ferreira, Rita ;

Neuparth, Maria J. ;

Marques, Franklim ;

Oliveira, Paulo J. ;

Duarte, Jose A. .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2006, 109 (02) :169-178

[7]

Exercise as a beneficial adjunct therapy during Doxorubicin treatment-Role of mitochondria in cardioprotection [J].

Ascensao, Antonio ;

Oliveira, Paulo J. ;

Magalhaes, Jose .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2012, 156 (01) :4-10

[8]

Myocardial infarction in mice alters sarcomeric function via post-translational protein modification [J].

Avner, Benjamin S. ;

Shioura, Krystyna M. ;

Scruggs, Sarah B. ;

Grachoff, Milana ;

Geenen, David L. ;

Helseth, Donald L., Jr. ;

Farjah, Mariam ;

Goldspink, Paul H. ;

Solaro, R. John .

MOLECULAR AND CELLULAR BIOCHEMISTRY, 2012, 363 (1-2) :203-215

[9]

H2O2 alters rat cardiac sarcomere function and protein phosphorylation through redox signaling [J].

Avner, Benjamin S. ;

Hinken, Aaron C. ;

Yuan, Chao ;

Solaro, R. John .

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2010, 299 (03) :H723-H730

[10]

Sympathetic hyperactivity differentially affects skeletal muscle mass in developing heart failure: role of exercise training [J].

Bacurau, Aline V. N. ;

Jardim, Maira A. ;

Ferreira, Julio C. B. ;

Bechara, Luiz R. G. ;

Bueno, Carlos R., Jr. ;

Alba-Loureiro, Tatiana C. ;

Negrao, Carlos E. ;

Casarini, Dulce E. ;

Curi, Rui ;

Ramires, Paulo R. ;

Moriscot, Anselmo S. ;

Brum, Patricia C. .

JOURNAL OF APPLIED PHYSIOLOGY, 2009, 106 (05) :1631-1640

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