Seroepidemiology of Middle East respiratory syndrome (MERS) coronavirus in Saudi Arabia (1993) and Australia (2014) and characterisation of assay specificity

被引：73

作者：

Hemida, M. G. ^{[1
,2
]}

Perera, R. A. ^{[3
,4
]}

Al Jassim, R. A. ^{[5
]}

Kayali, G. ^{[6
]}

Siu, L. Y. ^{[7
]}

Wang, P. ^{[7
,8
]}

Chu, K. W. ^{[3
,4
]}

Perlman, S. ^{[9
]}

Ali, M. A. ^{[10
]}

Alnaeem, A. ^{[11
]}

Guan, Y. ^{[3
,4
]}

Poon, L. L. ^{[3
,4
]}

Saif, L. ^{[12
]}

Peiris, M. ^{[3
,4
,7
]}

机构：

[1] King Faisal Univ, Coll Vet Med, Dept Microbiol & Parasitol, Al Hasa, Saudi Arabia

[2] Kaferelsheik Univ, Dept Virol, Fac Vet Med, Kaferelsheik, Egypt

[3] Univ Hong Kong, Influenza Res Ctr, Hong Kong, Hong Kong, Peoples R China

[4] Univ Hong Kong, Sch Publ Hlth, Hong Kong, Hong Kong, Peoples R China

[5] Univ Queensland, Fac Sci, Sch Agr & Food Sci, Gatton, Australia

[6] St Jude Childrens Res Hosp, Memphis, TN 38105 USA

[7] Univ Hong Kong, HKU Pasteur Pole, Hong Kong, Hong Kong, Peoples R China

[8] Chinese Acad Sci Univ Tokyo Joint Lab Struct Viro, Key Lab Prot & Peptide Pharmaceut, Beijing, Peoples R China

[9] Univ Iowa, Dept Microbiol, Iowa City, IA 52242 USA

[10] Natl Res Ctr, Div Environm Res, Giza, Egypt

[11] King Faisal Univ, Coll Vet Med, Dept Clin Studies, Al Hufuf, Saudi Arabia

[12] OARDC Ohio State Univ, Wooster, OH USA

来源：

EUROSURVEILLANCE | 2014年 / 19卷 / 23期

基金：

美国国家卫生研究院;

关键词：

DROMEDARY CAMELS; ANTIBODIES; INFECTION;

D O I：

10.2807/1560-7917.ES2014.19.23.20828

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The pseudoparticle virus neutralisation test (ppNT) and a conventional microneutralisation (MN) assay are specific for detecting antibodies to Middle East respiratory syndrome coronavirus (MERS-CoV) when used in seroepidemiological studies in animals. Genetically diverse MERS-CoV appear antigenically similar in MN tests. We confirm that MERS-CoV was circulating in dromedaries in Saudi Arabia in 1993. Preliminary data suggest that feral Australian dromedaries may be free of MERS-CoV but larger confirmatory studies are needed.

引用

页码：2 / 7

页数：6

共 22 条

[1]

Alagaili AN, 2014, MBIO, V5, DOI [10.1128/mBio.00884-14, 10.1128/mBio.01482-14]

[2] Middle East Respiratory Syndrome Coronavirus Antibody Reactors Among Camels in Dubai, United Arab Emirates, in 2005 [J].

Alexandersen, S. ;

Kobinger, G. P. ;

Soule, G. ;

Wernery, U. .

TRANSBOUNDARY AND EMERGING DISEASES, 2014, 61 (02) :105-108

[3]

*AUSTR GOV, NAT FER CAM ACT PLAN

[4] Examination of seroprevalence of coronavirus HKU1 infection with S protein-based ELISA and neutralization assay against viral spike pseudotyped virus [J].

Chan, C. M. ;

Tse, Herman ;

Wong, S. S. Y. ;

Woo, P. C. Y. ;

Lau, S. K. P. ;

Chen, L. ;

Zheng, B. J. ;

Huang, J. D. ;

Yuen, K. Y. .

JOURNAL OF CLINICAL VIROLOGY, 2009, 45 (01) :54-60

[5] MERS Coronaviruses in Dromedary Camels, Egypt [J].

Chu, Daniel K. W. ;

Poon, Leo L. M. ;

Gomaa, Mokhtar M. ;

Shehata, Mahmoud M. ;

Perera, Ranawaka A. P. M. ;

Abu Zeid, Dina ;

El Rifay, Amira S. ;

Siu, Lewis Y. ;

Guan, Yi ;

Webby, Richard J. ;

Ali, Mohamed A. ;

Peiris, Malik ;

Kayali, Ghazi .

EMERGING INFECTIOUS DISEASES, 2014, 20 (06) :1049-1053

[6]

CORMAN VM, 2014, EMERG INFECT DIS

[7] Middle East respiratory syndrome coronavirus in dromedary camels: an outbreak investigation [J].

Haagmans, Bart L. ;

Al Dhahiry, Said H. S. ;

Reusken, Chantal B. E. M. ;

Raj, V. Stalin ;

Galiano, Monica ;

Myers, Richard ;

Godeke, Gert-Jan ;

Jonges, Marcel ;

Farag, Elmoubasher ;

Diab, Ayman ;

Ghobashy, Hazem ;

Alhajri, Farhoud ;

Al-Thani, Mohamed ;

Al-Marri, Salih A. ;

Al Romaihi, Hamad E. ;

Al Khal, Abdullatif ;

Bermingham, Alison ;

Osterhaus, Albert D. M. E. ;

AlHajri, Mohd M. ;

Koopmans, Marion P. G. .

LANCET INFECTIOUS DISEASES, 2014, 14 (02) :140-145

[8]

HEMIDA MG, 2014, EMERG INFECT DIS

[9]

Hemida MG, 2013, EURO SURVEILL, V18, P20659

[10] ANTIGENIC RELATIONSHIPS AMONG HOMOLOGOUS STRUCTURAL POLYPEPTIDES OF PORCINE, FELINE, AND CANINE CORONAVIRUSES [J].

HORZINEK, MC ;

LUTZ, H ;

PEDERSEN, NC .

INFECTION AND IMMUNITY, 1982, 37 (03) :1148-1155

← 1 2 3 →