Pseudomonas aeruginosa lipopolysaccharides and pathogenesis

被引:45
作者
Goldberg, JB [1 ]
Pier, GB [1 ]
机构
[1] HARVARD UNIV,BRIGHAM & WOMENS HOSP,SCH MED,DEPT MED,CHANNING LAB,BOSTON,MA 02115
关键词
D O I
10.1016/S0966-842X(97)82911-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Pseudomonas aeruginosa lipopolysaccharide (LPS) plays a key role in pathogenesis. In acute infections, a smooth LPS protects the organism from complement-mediated killing and, during chronic lung infections, an altered rough LPS helps the organism evade host defense mechanisms.
引用
收藏
页码:490 / 494
页数:5
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