Of mice and women

被引：5

作者：

Foulkes, WD ^{[1
]}

机构：

[1] McGill Univ, Program Canc Genet, Dept Oncol, Montreal, PQ H3G 1A4, Canada

[2] McGill Univ, Dept Human Genet, Montreal, PQ H3G 1A4, Canada

来源：

CANCER CELL | 2002年 / 1卷 / 01期

关键词：

D O I：

10.1016/S1535-6108(02)00021-1

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Transgenic mouse model faithfully reproduces human ovarian carcinoma and offers new opportunities, for understanding the natural history of this frequently fatal disease.

引用

页码：11 / 12

页数：2

共 9 条

[1] Clinicopathologic features of BRCA-linked and sporadic ovarian cancer [J].

Boyd, J ;

Sonoda, Y ;

Federici, MG ;

Bogomolniy, F ;

Rhei, E ;

Maresco, DL ;

Saigo, PE ;

Almadrones, LA ;

Barakat, RR ;

Brown, CL ;

Chi, DS ;

Curtin, JP ;

Poynor, EA ;

Hoskins, WJ .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2000, 283 (17) :2260-2265

[2] Comparison of mutations of Ki-RAS and p53 immunoreactivity in borderline and malignant epithelial ovarian tumors [J].

Caduff, RF ;

Svoboda-Newman, SM ;

Ferguson, AW ;

Johnston, CN ;

Frank, TS .

AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1999, 23 (03) :323-328

[3] The cell of origin of ovarian epithelial tumors and the ovarian surface epithelium dogma: Does the emperor have no clothes? [J].

Dubeau, L .

GYNECOLOGIC ONCOLOGY, 1999, 72 (03) :437-442

[4] Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer [J].

McGuire, WP ;

Hoskins, WJ ;

Brady, MF ;

Kucera, PR ;

Partridge, EE ;

Look, KY ;

ClarkePearson, DL ;

Davidson, M .

NEW ENGLAND JOURNAL OF MEDICINE, 1996, 334 (01) :1-6

[5] BRCA1 and BRCA2 mutation analysis of 208 Ashkenazi Jewish women with ovarian cancer [J].

Moslehi, R ;

Chu, W ;

Karlan, B ;

Fishman, D ;

Risch, H ;

Fields, A ;

Smotkin, D ;

Ben-David, Y ;

Rosenblatt, J ;

Russo, D ;

Schwartz, P ;

Tung, N ;

Warner, E ;

Rosen, B ;

Friedman, J ;

Brunet, JS ;

Narod, SA .

AMERICAN JOURNAL OF HUMAN GENETICS, 2000, 66 (04) :1259-1272

[6] Induction of ovarian cancer by defined multiple genetic changes in a mouse model system [J].

Orsulic, S ;

Li, Y ;

Soslow, RA ;

Vitale-Cross, LA ;

Gutkind, JS ;

Varmus, HE .

CANCER CELL, 2002, 1 (01) :53-62

[7]

Silva EG, 1997, MODERN PATHOL, V10, P879

[8] Microarray analysis of gene expression mirrors the biology of an ovarian cancer model [J].

Tonin, PN ;

Hudson, TJ ;

Rodier, F ;

Bossolasco, M ;

Lee, PD ;

Novak, J ;

Manderson, EN ;

Provencher, D ;

Mes-Masson, AM .

ONCOGENE, 2001, 20 (45) :6617-6626

[9] Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation [J].

Xu, XL ;

Wagner, KU ;

Larson, D ;

Weaver, Z ;

Li, CL ;

Ried, T ;

Hennighausen, L ;

Wynshaw-Boris, A ;

Deng, CX .

NATURE GENETICS, 1999, 22 (01) :37-43

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