A convergent approach to functionalised alkynes

被引：29

作者：

Boivin, J

Huppe, S

Zard, SZ

机构：

[1] ECOLE POLYTECH,ORGAN SYNTH LAB,CNRS,F-91128 PALAISEAU,FRANCE

[2] CNRS,INST CHIM SUBST NAT,F-91198 GIF SUR YVETTE,FRANCE

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 48期

关键词：

D O I：

10.1016/S0040-4039(96)02015-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Knoevenagel type condensation of 4-unsubstituted isoxazolinones with ketones or aldehydes followed by Michael addition of a nucleophile - hydride, cyanide, or phosphite- and exposure of the adduct to sodium nitrite/aqueous acetic acid and ferrous sulfate gives variously functionalised alkynes. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：8735 / 8738

页数：4

共 14 条

[1]

BECCALLI EM, 1988, SYNTHESIS-STUTTGART, P886

[2]

BENEFRAIM DA, 1978, CHEM CARBON CARBON T, P755

[3] MASTERING BETA-KETO-ESTERS [J].