RNA silencing: The genome's immune system

被引：300

作者：

Plasterk, RHA ^{[1
]}

机构：

[1] Netherlands Inst Dev Biol, Hubrecht Lab, Ctr Biomed Genet, NL-3584 CT Utrecht, Netherlands

来源：

SCIENCE | 2002年 / 296卷 / 5571期

关键词：

D O I：

10.1126/science.1072148

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Genomes are databases sensitive to invasion by viruses. In recent years, a defense mechanism has been discovered, which turns out to be conserved among eukaryotes. The system can be compared to the immune system in several ways: It has specificity against foreign elements and the ability to amplify and raise a massive response against an invading nucleic acid. The latter property is beginning to be understood at the molecular level.

引用

页码：1263 / 1265

页数：3

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