Relaxation and diffusion of perfluorocarbon gas mixtures with oxygen for lung MRI

被引：22

作者：

Chang, Yulin V. ^{[1
]}

Conradi, Mark S.

机构：

[1] Washington Univ, Dept Phys, St Louis, MO 63130 USA

[2] Washington Univ, Dept Radiol, St Louis, MO 63130 USA

来源：

JOURNAL OF MAGNETIC RESONANCE | 2006年 / 181卷 / 02期

关键词：

perfluorocarbon gas; hyperpolarized gas; lung; diffusion; relaxation;

D O I：

10.1016/j.jmr.2006.04.003

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We report measurements of free diffusivity Do and relaxation times T-1 and T-2 for pure C2F6 and C3F8 and their mixtures with oxygen. A simplified relaxation theory is presented and used to fit the data. The results enable spatially localized relaxation time measurements to determine the local gas concentration in lung MR images, so the free diffusivity Do is then known. Comparison of the measured diffusion to Do will express the extent of diffusion restriction and allow the local surface-to-volume ratio to be found. (c) 2006 Elsevier Inc. All rights reserved.

引用

页码：191 / 198

页数：8

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