Experiences with vaccination in countries endemically infected with highly pathogenic avian influenza: the Food and Agriculture Organization perspective

被引:64
作者
Domenech, J. [1 ]
Dauphin, G. [1 ]
Rushton, J. [1 ]
McGrane, J.
Lubroth, J. [1 ]
Tripodi, A. [1 ]
Gilbert, J.
Sims, L. D.
机构
[1] FAO, I-00100 Rome, Italy
来源
REVUE SCIENTIFIQUE ET TECHNIQUE-OFFICE INTERNATIONAL DES EPIZOOTIES | 2009年 / 28卷 / 01期
关键词
Avian influenza; Control; H5N1; Prevention; Vaccination; MOUTH-DISEASE; H5N1; OUTBREAK; RESPONSES; COSTS;
D O I
10.20506/rst.28.1.1865
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Vaccination has been used extensively for the control and prevention of highly pathogenic avian influenza (HPAI) caused by viruses of the H5N1 subtype in endemically infected countries. The Food and Agriculture Organization views vaccination as a legitimate aid in the control and prevention of infection and disease caused by HPAI viruses but does not see it as a panacea. Vaccination should be used as just one in a number of measures used together to reduce the effect and risk of infection. It will be required for a considerable time in endemically infected countries. The methods used in Vietnam in implementing blanket vaccination against H5N1 HPAI viruses demonstrate the steps that should be considered when introducing vaccination. So far, it has not been possible to determine the precise effect of vaccination in endemically infected countries because it has been used in combination with other measures. Well managed vaccination campaigns will reduce the incidence of infection in poultry and therefore reduce the risk to humans from these viruses. Vaccination was implemented to protect both poultry and humans, with a major goal being to reduce the risk of emergence of a human influenza pandemic virus. Economic analysis of vaccination should focus on cost-effectiveness of proposed strategies. Ex-ante and ex-post evaluation of vaccination campaigns should take into account the benefits generated in the poultry sector and for human health.
引用
收藏
页码:293 / 305
页数:13
相关论文
共 34 条
  • [1] Capua I, 2007, DEV BIOLOGICALS, V130, P137
  • [2] CAST, 2007, AV INFL VACC FOC H5N
  • [3] Chen Hualan, 2008, V27
  • [4] Dinh PN, 2006, EMERG INFECT DIS, V12, P1841
  • [5] DUAN L, 2008, VIROLOGY, V20
  • [6] ELLIS PR, 1972, 11 READ U DEP AGR ST, P77
  • [7] Ellis TM, 2006, DEV BIOLOGICALS, V124, P133
  • [8] *FAO, 2007, FAO OIE WHO TECHN WO
  • [9] FAO, 2004, REC PREV CONTR ER HI
  • [10] *FAO, 2008, UND AV INFL