Long-term consumption of fermented dairy products over 6 months increases HDL cholesterol

被引:157
作者
Kiessling, G [1 ]
Schneider, J [1 ]
Jahreis, G [1 ]
机构
[1] Univ Jena, Inst Nutr Sci, D-07743 Jena, Germany
关键词
probiotic yoghurt; Lactobacillus acidophilus 145; Bifidobacterium longum 913; blood lipids; cholesterol; SCFA;
D O I
10.1038/sj.ejcn.1601399
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Objective: Assessment of the hypocholesterolaemic effect of yoghurt supplemented with Lactobacillus acidophilus 145 and Bifidobacterium longum 913 in women. Design: The cross-over study consisted of three periods (7 weeks each): first period, control yoghurt for all 29 women; second period, probiotic yoghurt for 18 women, control yoghurt for I I women; third period, the reverse of that in the second period. Setting: Department of Nutritional Physiology, Institute of Nutritional Science, Friedrich Schiller University, Jena. Subjects: Twenty-nine healthy women, aged 19-56y. Fifteen of these were normocholesterolaemic and 14 women were hypercholesterolaemic. Intervention: Yoghurt (300g) daily containing 3.5% fat and starter cultures of Streptococcus thermophilus and L. lactis. Probiotic yoghurt was the control yoghurt enriched with L. acidophilus 145, B. longum 913 and 1% oligofructose (synbiotic). Results: The mean serum concentration of total cholesterol and the LDL cholesterol was not influenced by the synbiotic (P > 0.05). The HDL concentration increased significantly by 0.3mmol/l (P = 0.002). The ratio of LDL/HDL cholesterol decreased from 3.24 to 2.48 (P = 0.001). Conclusions: The long-term daily consumption of 300g yoghurt over a period of 21 weeks (control and synbiotic) increased the serum concentration of HDL cholesterol and lead to the desired improvement of the LDL/HDL cholesterol ratio.
引用
收藏
页码:843 / 849
页数:7
相关论文
共 39 条
[1]  
AGERBAEK M, 1995, EUR J CLIN NUTR, V49, P346
[2]   Effect of 8 week intake of probiotic milk products on risk factors for cardiovascular diseases [J].
Agerholm-Larsen, L ;
Raben, A ;
Haulrik, N ;
Hansen, AS ;
Manders, M ;
Astrup, A .
EUROPEAN JOURNAL OF CLINICAL NUTRITION, 2000, 54 (04) :288-297
[3]   Serum lipoprotein cholesterol and triglyceride concentrations in pigs fed diets containing fish oil, milkfat, olive oil and coconut oil [J].
Allan, FJ ;
Thompson, KG ;
James, KAC ;
Manktelow, BW ;
Koolaard, JP ;
Johnson, RN ;
McNutt, PV .
NUTRITION RESEARCH, 2001, 21 (05) :785-795
[4]   Effect of fermented milk (yogurt) containing Lactobacillus acidophilus L1 on serum cholesterol in hypercholesterolemic humans [J].
Anderson, JW ;
Gilliland, SE .
JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION, 1999, 18 (01) :43-50
[5]  
Bengstsson S, 2001, MOD SPRAK, V95, P1
[6]   Robiotics, prebiotics or 'conbiotics'? [J].
Berg, RD .
TRENDS IN MICROBIOLOGY, 1998, 6 (03) :89-92
[7]   Evaluation of the effects of a new fermented milk product (Gaio) on primary hypercholesterolemia [J].
Bertolami, MC ;
Faludi, AA ;
Batlouni, M .
EUROPEAN JOURNAL OF CLINICAL NUTRITION, 1999, 53 (02) :97-101
[8]   Bile salt deconjugation and cholesterol removal from media by Lactobacillus casei [J].
Brashears, MM ;
Gilliland, SE ;
Buck, LM .
JOURNAL OF DAIRY SCIENCE, 1998, 81 (08) :2103-2110
[9]   COMPARISONS OF FRESHLY ISOLATED STRAINS OF LACTOBACILLUS-ACIDOPHILUS OF HUMAN INTESTINAL ORIGIN FOR ABILITY TO ASSIMILATE CHOLESTEROL DURING GROWTH [J].
BUCK, LM ;
GILLILAND, SE .
JOURNAL OF DAIRY SCIENCE, 1994, 77 (10) :2925-2933
[10]  
CHAE GT, 1995, NEW MED J, V38, P1