Sheets, ribbons and tubules - how organelles get their shape

被引：119

作者：

Voeltz, Gia K. ^{[1
]}

Prinz, William A. ^{[1
]}

机构：

[1] NIDDK, Lab Cell Biochem & Biol, NIH, US Dept Hlth & Human Serv, Bethesda, MD 20892 USA

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2007年 / 8卷 / 03期

关键词：

D O I：

10.1038/nrm2119

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Most membrane-bound organelles have elaborate, dynamic shapes and often include regions with distinct morphologies. These complex structures are relatively conserved throughout evolution, which indicates that they are important for optimal organelle function. Various mechanisms of determining organelle shape have been proposed-proteins that stabilize highly curved membranes, the tethering of organelles to other cellular components and the regulation of membrane fission and fusion might all contribute.

引用

页码：258 / 264

页数：7

共 54 条

[1] AN INVESTIGATION OF MITOCHONDRIAL INNER MEMBRANES BY RAPID-FREEZE DEEP-ETCH TECHNIQUES [J].

ALLEN, RD ;

SCHROEDER, CC ;

FOK, AK .

JOURNAL OF CELL BIOLOGY, 1989, 108 (06) :2233-2240

[2] The modulation in subunits e and g amounts of yeast ATP synthase modifies mitochondrial cristae morphology [J].

Arselin, G ;

Vaillier, J ;

Salin, B ;

Schaeffer, J ;

Giraud, MF ;

Dautant, A ;

Brèthes, D ;

Velours, J .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (39) :40392-40399

[3] A new paradigm for membrane-organizing and -shaping scaffolds [J].

Bauer, Manuel ;

Pelkmans, Lucas .

FEBS LETTERS, 2006, 580 (23) :5559-5564

[4] ASSEMBLY OF THE ENDOPLASMIC-RETICULUM PHOSPHOLIPID-BILAYER - THE PHOSPHATIDYLCHOLINE TRANSPORTER [J].

BISHOP, WR ;

BELL, RM .

CELL, 1985, 42 (01) :51-60

[5] The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast [J].

Bleazard, W ;

McCaffery, JM ;

King, EJ ;

Bale, S ;

Mozdy, A ;

Tieu, Q ;

Nunnari, J ;

Shaw, JM .

NATURE CELL BIOLOGY, 1999, 1 (05) :298-304

[6] Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution [J].

Burkhardt, JK ;

Echeverri, CJ ;

Nilsson, T ;

Vallee, RB .

JOURNAL OF CELL BIOLOGY, 1997, 139 (02) :469-484

[7] Ultrafast glycerophospholipid-selective transbilayer motion mediated by a protein in the endoplasmic reticulum membrane [J].

Buton, X ;

Morrot, G ;

Fellmann, P ;

Seigneuret, M .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (12) :6651-6657

[8] A common lipid links Mfn-mediated mitochondrial fusion and SNARE-regulated exocytosis [J].

Choi, Seok-Yong ;

Huang, Ping ;

Jenkins, Gary M. ;

Chan, David C. ;

Schiller, Juergen ;

Frohman, Michael A. .

NATURE CELL BIOLOGY, 2006, 8 (11) :1255-U29

[9] OPA1 requires mitofusin 1 to promote mitochondrial fusion [J].

Cipolat, S ;

de Brito, OM ;

Dal Zilio, B ;

Scorrano, L .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (45) :15927-15932

[10]

CLUETT EB, 1992, J CELL SCI, V103, P773

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