Vibrio vulnificus induces macrophage apoptosis in vitro and in vivo

被引：36

作者：

Kashimoto, T

Ueno, S

Hanajima, M

Hayashi, H

Akeda, Y

Miyoshi, S

Hongo, T

Honda, T

Susa, N

机构：

[1] Kitasato Univ, Sch Vet Med & Anim Sci, Lab Vet Publ Hlth, Towada, Aomori 0348628, Japan

[2] Osaka Univ, Res Inst Microbial Dis, Dept Bacterial Infect, Suita, Osaka 5650871, Japan

[3] Okayama Univ, Fac Pharmaceut Sci, Okayama 7008530, Japan

[4] Kurashiki Cent Hosp, Dept Lab Med, Okayama 7108602, Japan

来源：

INFECTION AND IMMUNITY | 2003年 / 71卷 / 01期

关键词：

D O I：

10.1128/IAI.71.1.533-535.2003

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In this study, we compared the apoptotic activities of clinical and environmental isolates of Vibrio vulnificus toward macrophages in vitro and in vivo. The clinical isolates induced apoptosis in macrophage-like cells in vitro and in macrophages in vivo. This suggests that macrophage apoptosis may be important for the clinical virulence of V. vulnificus.

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页码：533 / 535

页数：3

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