Spin trapping of superoxide in the presence of β-cyclodextrins

被引：51

作者：

Karoui, H ^{[1
]}

Rockenbauer, A

Pietri, S

Tordo, P

机构：

[1] CNRS, UMR 6517, F-13397 Marseille 20, France

[2] Univ Aix Marseille 1, Fac Sci St Jerome, F-13397 Marseille, France

[3] Univ Aix Marseille 3, Fac Sci St Jerome, F-13397 Marseille 20, France

[4] Inst Chem, Chem Res Ctr, H-125 Budapest, Hungary

来源：

CHEMICAL COMMUNICATIONS | 2002年 / 24期

关键词：

D O I：

10.1039/b209787g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The trapping of superoxide anion with DMPOdagger and DEPMPOdagger has been carried out in the presence of a methylated P-cyclodextrin, Me-beta-CDdagger; inclusion of the spin adducts in the cavity of Me-beta-CD resulted in a seven-fold increase of their half-life (t(1/2) = 96 min for DEPMPO-superoxide spin adduct) and in their protection towards glutathione peroxidase (Gpx) and also ascorbate anion in the case of DEPMPO.

引用

页码：3030 / 3031

页数：2

共 25 条

[1]

EBEL C, 1985, NOUV J CHIM, V9, P479

[2] 105-NITROXIDE - REDUCTION KINETICS OF A NITROXIDE RADICAL BY MEANS OF ASCORBIC-ACID IN THE PRESENCE OF BETA-CYCLODEXTRIN [J].