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Recent progress in multiple sequence alignment: a survey

被引：219
作者：
Notredame, C [1 ]
机构：
[1] UMR Informat Genet & Struct 1889, F-13006 Marseille, France
来源：
PHARMACOGENOMICS | 2002年 / 3卷 / 01期
关键词：
BLAST; hidden Markov model; multiple sequence alignment; T-Coffee;
D O I：
10.1517/14622416.3.1.131
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The assembly of a multiple sequence alignment (MSA) has become one of the most common tasks when dealing with sequence analysis. Unfortunately, the wide range of available methods and the differences in the results given by these methods makes it hard for a non-specialist to decide which program is best suited for a given purpose. In this review we briefly describe existing techniques and expose the potential strengths and weaknesses of the most widely used multiple alignment packages.
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页码：131 / 144
页数：14
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