Nosocomial influenza outbreak in a geriatrics department - Effectiveness of preventive measures

被引:12
作者
Andrieu, Anne-Gaelle
Paute, Jocelyne
Glomot, Laure
Jarlier, Vincent
Belmin, Joel
机构
[1] Hop Charles Foix, Serv Geriatrie, F-94205 Ivry, France
[2] Hop Charles Foix, Equipe Operat Hyg, F-94205 Ivry, France
[3] Univ Paris 06, F-94205 Ivry, France
[4] Hop La Pitie Salpetriere, Bacteriol Lab, F-75013 Paris, France
来源
PRESSE MEDICALE | 2006年 / 35卷 / 10期
关键词
D O I
10.1016/S0755-4982(06)74830-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective > To describe a nosocomiol influenza outbreak and the pharmacologic and nornpharmacologic control measures implemented in a hospital word with beds for acute geriatric care and rehabilitation care. Methods > Descriptive survey conducted in the geriatrics department of a university hospital. An influenza outbreak occured in February 2005 in 2 of the deportment 3 separate units. The study concerned all patients in the 2 affected units (A and B) present during the outbreak, as well as all deportment staff. once cases of influenza were confirmed, elderly patients in contact with influenza patients received chemoprophyloxis with oseltamivir when it become available. Results > Thirty-eight (76 %) patients and 62 (38 %) staff members hod been vaccinated. The time from the initial symptoms of the first case until Implementation of control measures was 7 days in unit A but only I day in unit B, -and chemoprophylaxis of contact patients began in 9 days and 24 hours respectively. The attack rote was 38 % in the 38 vaccinated patients and 29% in the 14 unvaccinated patients (NS). All cases met the definition of nosocomial infection. No deaths imputable to influenza occurred during the outbreak. The implementation of the nonpharmacologic measures aimed at preventing spread of the outbreak presented no particular difficulty except for compliance with geographic isolation of some patients with dementia and influenza. The difference between the attack rates for the two sectors (48 % for unit A and 28% for unit B) suggests that the preventive measures were effective. Tolerance to chemoprophylaxis with oseltamivir was good. Conclusion > This study confirmed that influenza con affect elderly hospital patients, even those in whom the vaccination rote is high and that rapid detection of the outbreak and immediate implementation of pharmacologic and nonpharmacologic preventive measures can limit its spread.
引用
收藏
页码:1419 / 1426
页数:8
相关论文
共 25 条
[1]   Use of oseltamivir during influenza outbreaks in Ontario nursing homes, 1999-2000 [J].
Bowles, SK ;
Lee, W ;
Simor, AE ;
Vearncombe, M ;
Loeb, M ;
Tamblyn, S ;
Fearon, M ;
Li, Y ;
McGeer, A .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2002, 50 (04) :608-616
[2]  
CARLET J, 2004, PREVENTION RISQUE IN
[3]   Effects of influenza vaccination of health-care workers on mortality of elderly people in long-term care: a randomised controlled trial [J].
Carman, WF ;
Elder, AG ;
Wallace, LA ;
McAulay, K ;
Walker, A ;
Murray, GD ;
Stott, DJ .
LANCET, 2000, 355 (9198) :93-97
[4]   AN OUTBREAK OF INFLUENZA-A (H3N2) IN A WELL IMMUNIZED NURSING-HOME POPULATION [J].
COLES, FB ;
BALZANO, GJ ;
MORSE, DL .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 1992, 40 (06) :589-592
[5]   Influenza vaccination and antiviral therapy - Is there a role for concurrent administration in the institutionalised elderly? [J].
Drinka, PJ .
DRUGS & AGING, 2003, 20 (03) :165-174
[6]   Policies and practices for improving influenza immunization rates among healthcare workers [J].
Goldstein, AO ;
Kincade, JE ;
Gamble, G ;
Bearman, RS .
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2004, 25 (11) :908-911
[7]   Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals [J].
Goronzy, JJ ;
Fulbright, JW ;
Crowson, CS ;
Poland, GA ;
O'Fallon, WM ;
Weyand, CM .
JOURNAL OF VIROLOGY, 2001, 75 (24) :12182-12187
[8]   THE EFFICACY OF INFLUENZA VACCINATION IN ELDERLY INDIVIDUALS - A RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED TRIAL [J].
GOVAERT, TME ;
THIJS, CTMCN ;
MASUREL, N ;
SPRENGER, MJW ;
DINANT, GJ ;
KNOTTNERUS, JA .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1994, 272 (21) :1661-1665
[9]   Time to peak serum antibody response to influenza vaccine in the elderly [J].
Gross, PA ;
Russo, C ;
Teplitzky, M ;
Dran, S ;
Cataruozolo, P ;
Munk, G .
CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, 1996, 3 (03) :361-362
[10]   THE EFFICACY OF INFLUENZA VACCINE IN ELDERLY PERSONS - A METAANALYSIS AND REVIEW OF THE LITERATURE [J].
GROSS, PA ;
HERMOGENES, AW ;
SACKS, HS ;
LAU, J ;
LEVANDOWSKI, RA .
ANNALS OF INTERNAL MEDICINE, 1995, 123 (07) :518-527