Sensitivity enhancement of DNA sensors by nanogold surface modification

被引：41

作者：

Liu, T ^{[1
]}

Tang, J ^{[1
]}

Jiang, L ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Lab Colloid & Interface Sci, Beijing 100080, Peoples R China

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 2002年 / 295卷 / 01期

基金：

中国国家自然科学基金;

关键词：

colloidal Au; DNA sensing; quartz crystal microbalanace;

D O I：

10.1016/S0006-291X(02)00628-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A novel amplified microgravimetric gene sensing system was developed using quartz crystal microbalance modified by gold nanoparticles anchored on its 1,6-hexanedithiol modified gold electrode surface, and ultrasensitive detection of DNA hybridization was accomplished at the level of at least 2 x 10(-16) M. (C) 2002 Elsevier Science (USA). All rights reserved.

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页码：14 / 16

页数：3

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