A new convenient preparation of thiol esters utilizing N-acylbenzotriazoles

被引：90

作者：

Katritzky, AR ^{[1
]}

Shestopalov, AA ^{[1
]}

Suzuki, K ^{[1
]}

机构：

[1] Univ Florida, Ctr Heterocycl Cpds, Dept Chem, Gainesville, FL 32611 USA

来源：

SYNTHESIS-STUTTGART | 2004年 / 11期

关键词：

benzotriazole methodology; N-acylbenzotriazoles; acylating agent; S-acylation; thiol esters;

D O I：

10.1055/s-2004-829126

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Diverse thiol esters were synthesized in good to excellent yields (76-99%) by reactions of thiophenol, benzyl mercaptan, ethyl mercaptoacetate, and mercaptoacetic acid with N-acylbenzotriazoles under mild conditions. These results demonstrate the utility of N-acylbenzotriazoles as mild S-acylating agents, especially when the corresponding acid chlorides are not readily available.

引用

页码：1806 / 1813

页数：8

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