Drinking Coffee Burns Hepatic Fat by Inducing Lipophagy Coupled With Mitochondrial β-Oxidation

被引：48

作者：

Ding, Wen-Xing ^{[1
]}

机构：

[1] Univ Kansas, Med Ctr, Dept Pharmacol Toxicol & Therapeut, Kansas City, KS 66160 USA

来源：

HEPATOLOGY | 2014年 / 59卷 / 04期

关键词：

CAFFEINE CONSUMPTION; LIPID-METABOLISM; LIVER; AUTOPHAGY; PHOSPHORYLATION; STEATOHEPATITIS; ASSOCIATION; EXPRESSION; FIBROSIS; GROWTH;

D O I：

10.1002/hep.26736

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

[No abstract available]

引用

页码：1235 / 1238

页数：4

共 20 条

[1]

Regular coffee but not espresso drinking is protective against fibrosis in a cohort mainly composed of morbidly obese European women with NAFLD undergoing bariatric surgery [J].

Anty, Rodolphe ;

Marjoux, Sophie ;

Iannelli, Antonio ;

Patouraux, Stephanie ;

Schneck, Anne-Sophie ;

Bonnafous, Stephanie ;

Gire, Camille ;

Amzolini, Anca ;

Ben-Amor, Imed ;

Saint-Paul, Marie-Christine ;

Marine-Barjoan, Eugenia ;

Pariente, Alexandre ;

Gugenheim, Jean ;

Gual, Philippe ;

Tran, Albert .

JOURNAL OF HEPATOLOGY, 2012, 57 (05) :1090-1096

[2]

Preventing lysosomal fat indigestion [J].

Cuervo, Ana Maria .

NATURE CELL BIOLOGY, 2013, 15 (06) :565-567

[3]

Autophagy Reduces Acute Ethanol-Induced Hepatotoxicity and Steatosis in Mice [J].

Ding, Wen-Xing ;

Li, Min ;

Chen, Xiaoyun ;

Ni, Hong-Min ;

Lin, Chih-Wen ;

Gao, Wentao ;

Lu, Binfeng ;

Stolz, Donna B. ;

Clemens, Dahn L. ;

Yin, Xiao-Ming .

GASTROENTEROLOGY, 2010, 139 (05) :1740-1752

[4]

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy [J].

Egan, Daniel F. ;

Shackelford, David B. ;

Mihaylova, Maria M. ;

Gelino, Sara ;

Kohnz, Rebecca A. ;

Mair, William ;

Vasquez, Debbie S. ;

Joshi, Aashish ;

Gwinn, Dana M. ;

Taylor, Rebecca ;

Asara, John M. ;

Fitzpatrick, James ;

Dillin, Andrew ;

Viollet, Benoit ;

Kundu, Mondira ;

Hansen, Malene ;

Shaw, Reuben J. .

SCIENCE, 2011, 331 (6016) :456-461

[5]

Association of Coffee Drinking with Total and Cause-Specific Mortality [J].

Freedman, Neal D. ;

Park, Yikyung ;

Abnet, Christian C. ;

Hollenbeck, Albert R. ;

Sinha, Rashmi .

NEW ENGLAND JOURNAL OF MEDICINE, 2012, 366 (20) :1891-1904

[6]

Pharmacological application of caffeine inhibits TGF-β-stimulated connective tissue growth factor expression in hepatocytes via PPARγ and SMAD2/3-dependent pathways [J].

Gressner, Olav A. ;

Lahme, Birgit ;

Rehbein, Katharina ;

Siluschek, Monika ;

Weiskirchen, Ralf ;

Gressner, Axel M. .

JOURNAL OF HEPATOLOGY, 2008, 49 (05) :758-767

[7]

Less Smad2 Is Good for You! A Scientific Update on Coffee's Liver Benefits [J].

Gressner, Olav A. .

HEPATOLOGY, 2009, 50 (03) :970-978

[8]

AMPK phosphorylation of raptor mediates a metabolic checkpoint [J].

Gwinn, Dana M. ;

Shackelford, David B. ;

Egan, Daniel F. ;

Mihaylova, Maria M. ;

Mery, Annabelle ;

Vasquez, Debbie S. ;

Turk, Benjamin E. ;

Shaw, Reuben J. .

MOLECULAR CELL, 2008, 30 (02) :214-226

[9]

TSC2 mediates cellular energy response to control cell growth and survival [J].

Inoki, K ;

Zhu, TQ ;

Guan, KL .

CELL, 2003, 115 (05) :577-590

[10]

Coffee Induces Expression of Glucuronosyltransferases by the Aryl Hydrocarbon Receptor and Nrf2 in Liver and Stomach [J].

Kalthoff, Sandra ;

Ehmer, Ursula ;

Freiberg, Nicole ;

Manns, Michael P. ;

Strassburg, Christian P. .

GASTROENTEROLOGY, 2010, 139 (05) :1699-+

← 1 2 →