Intracellular lifestyle of Brucella spp.: Common genes with other animal pathogens, plant pathogens, and endosymhionts

被引:70
作者
Ugalde, RA [1 ]
机构
[1] Univ Nacl Gen San Martin, Inst Invest Biotecnol, RA-1650 San Martin, Buenos Aires, Argentina
关键词
Brucella spp; pathogenesis; intracellular multiplication;
D O I
10.1016/S1286-4579(99)00240-3
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Brucella spp. are intracellular pathogens that belong, like Agrobacterium, Rhizobium and Rickettsia, to the alpha-2-subgroup of proteobacteria. The genome organization of most Brucella spp. is characterized by the presence of two chromosomes. The intracellular lifestyle of Brucella, as well as the possible genes involved in pathogenesis and host cell signaling, are discussed, including the presence of genes with high similarity to those from other animal pathogens, plant pathogens and endosymbionts. (C) 1999 Editions scientifiques et medicales Elsevier SAS.
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页码:1211 / 1219
页数:9
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