Concise synthesis of a buffalo milk pentasaccharide derivative

被引：9

作者：

Gu, GF

Du, YG

Pan, JQ

机构：

[1] Acad Sinica, Ecoenvironm Sci Res Ctr, Beijing 100085, Peoples R China

[2] Peking Univ, Coll Chem & Mol Engn, Beijing 100871, Peoples R China

来源：

CARBOHYDRATE RESEARCH | 2002年 / 337卷 / 14期

基金：

中国国家自然科学基金;

关键词：

glycosylation; antigens; thioglycosides; oligosaccharides; regioselectivity;

D O I：

10.1016/S0008-6215(02)00131-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An efficient synthesis of buffalo milk pentasaccharide derivative via a 3 + 2 strategy is described. The use of a trisaccharide isopropyl thioglycoside as a latent glycosyl donor and the application of two well-defined regioselective glycosylations significantly simplified the target preparation. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

收藏

页码：1313 / 1317

页数：5

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