A novel synthesis of tricyclic-fused hydrindene-azetidinone compounds by sequential Mn(III)-promoted 4-exo-trig cyclization/radical aromatic substitution

被引：20

作者：

Cerreti, A ^{[1
]}

D'Annibale, A ^{[1
]}

Trogolo, C ^{[1
]}

Umani, F ^{[1
]}

机构：

[1] Univ Rome La Sapienza, Dipartimento Chim, CNR, Ctr Studio Chim Sostanze Organ Nat, I-00185 Rome, Italy

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 17期

关键词：

cyclization; azetidinones; manganese and compounds; radicals and radical reaction; polycyclic heterocyclic compounds;

D O I：

10.1016/S0040-4039(00)00364-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The 2-acyl-N-(2,2-diphenyl-1-ethenyl)-N-alkylacetamides reacted with excess Mn(III) affording tricyclic fused hydrindene-azetidinones in good yields, through a 4-exo-trig radical cyclization process, and further ring closure of the azetidinone via radical aromatic substitution. (C) 2000 Elsevier Science Ltd. All rights reserved.

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页码：3261 / 3264

页数：4

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