Bioactive and metal uptake studies of carboxymethyl chitosan-graft-D-glucuronic acid membranes for tissue engineering and environmental applications

被引：21

作者：

Jayakumar, R. ^{[1
,2
,3
]}

Rajkumar, M. ^{[4
]}

Freitas, H. ^{[4
]}

Kumar, P. T. Sudheesh ^{[1
]}

Nair, S. V. ^{[1
]}

Furuike, T. ^{[2
,3
]}

Tamura, H. ^{[2
,3
]}

机构：

[1] Amrita Inst Med Sci & Res Ctr, Amrita Ctr Nanosci, Amrita Viswa Vidyapeetha 682026, Kochi, India

[2] Kansai Univ, Fac Chem Mat & Bioengn, Osaka 5648680, Japan

[3] Kansai Univ, High Technol Res Ctr, Osaka 5648680, Japan

[4] Univ Coimbra, Ctr Funct Ecol, Dept Bot, P-3000455 Coimbra, Portugal

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2009年 / 45卷 / 02期

基金：

日本学术振兴会;

关键词：

Chitosan; Grafting; Bioactivity; Metal uptake studies; XRD studies; COMPOSITE SCAFFOLDS; IN-VITRO; CHITIN; EQUILIBRIUM; ADSORPTION; KINETICS;

D O I：

10.1016/j.ijbiomac.2009.04.016

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Carboxymethyl chitosan-graft-D-glucuronic acid (CMCS-g-D-GA) was prepared by grafting D-GA onto CMCS in the presence of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide(EDC) and then the membranes were made from it. In this work, the bioactivity studies Of CMCS-g-D-GA membranes were carried out and then characterized by SEM, CLSM, XRD and FT-IR. The CMCS-g-D-GA membranes were found to be bioactive. The adsorption of Ni2+, Zn2+ and Cu2+ ions onto CMCS-g-D-GA membranes has also been investigated. The maximum adsorption capacity of CMCS-g-D-GA for Ni2+, Zn2+ and Cu2+ was found to be 57, 56.4 and 70.2 mg/g, respectively. Hence, these membranes were useful for tissue engineering, environmental and water purification applications. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：135 / 139

页数：5

共 42 条

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