Laser and non-laser light sources for photodynamic therapy

被引：379

作者：

Brancaleon, L

Moseley, H ^{[1
]}

机构：

[1] Univ Dundee, Ninewells Hosp & Med Sch, Photobiol Unit, Dundee DD1 9SY, Scotland

[2] Univ Dundee, Ninewells Hosp & Med Sch, Dept Med Phys, Dundee DD1 9SY, Scotland

来源：

LASERS IN MEDICAL SCIENCE | 2002年 / 17卷 / 03期

关键词：

cancer treatment; light sources; photodynamic therapy (PDT); photosensitisers;

D O I：

10.1007/s101030200027

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Photodynamic therapy (PDT) is an anticancer combination therapy, which requires a photo-sensitiser, which tends to accumulate preferentially in the tumour, and light. Historically large, complex lasers have been used to carry out PDT treatment. Nowadays there is a wide range of coherent and non-coherent sources that can be used. This paper considers the important characteristics of light sources for PDT, including dye lasers pumped by argon or metal vapour lasers and frequency-doubled Nd:YAG lasers. Non-laser sources including tungsten filament, xenon arc, metal halide and fluorescent lamps are also discussed. New exiciting developments such as LEDs and femtosecond lasers are also reviewed. The relative merits of laser and non-laser sources are critically examined.

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页码：173 / 186

页数：14

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