Immunization with DNA vaccines in early life: advantages and limitations as compared to conventional vaccines

被引:21
作者
Siegrist, CA [1 ]
Lambert, PH [1 ]
机构
[1] UNIV GENEVA,WHO,COLLABORATING CTR NEONATAL VACCINOL,DEPT PEDIAT,CH-1211 GENEVA 4,SWITZERLAND
来源
SPRINGER SEMINARS IN IMMUNOPATHOLOGY | 1997年 / 19卷 / 02期
关键词
D O I
10.1007/BF00870271
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
[No abstract available]
引用
收藏
页码:233 / 243
页数:11
相关论文
共 29 条
[1]   Immune response in mice following immunization with DNA encoding fragment C of tetanus toxin [J].
Anderson, R ;
Gao, XM ;
Papakonstantinopoulou, A ;
Roberts, M ;
Dougan, G .
INFECTION AND IMMUNITY, 1996, 64 (08) :3168-3173
[2]  
Ballas ZK, 1996, J IMMUNOL, V157, P1840
[3]   Partial correction of the TH2/TH1 imbalance in neonatal murine responses to vaccine antigens through selective adjuvant effects [J].
Barrios, C ;
Brandt, C ;
Berney, M ;
Lambert, PH ;
Siegrist, CA .
EUROPEAN JOURNAL OF IMMUNOLOGY, 1996, 26 (11) :2666-2670
[4]   Neonatal and early life immune responses to various forms of vaccine antigens qualitatively differ from adult responses: Predominance of a Th2-biased pattern which persists after adult boosting [J].
Barrios, C ;
Brawand, P ;
Berney, M ;
Brandt, C ;
Lambert, PH ;
Siegrist, CA .
EUROPEAN JOURNAL OF IMMUNOLOGY, 1996, 26 (07) :1489-1496
[5]  
BURSTEIN HJ, 1992, J IMMUNOL, V148, P3687
[6]   Immunization with plasmid DNA encoding for the measles virus hemagglutinin and nucleoprotein leads to humoral and cell-mediated immunity [J].
Cardoso, AI ;
BlixenkroneMoller, M ;
Fayolle, J ;
Liu, M ;
Buckland, R ;
Wild, TF .
VIROLOGY, 1996, 225 (02) :293-299
[7]   DNA-BASED IMMUNIZATION INDUCES CONTINUOUS SECRETION OF HEPATITIS-B SURFACE-ANTIGEN AND HIGH-LEVELS OF CIRCULATING ANTIBODY [J].
DAVIS, HL ;
MICHEL, ML ;
WHALEN, RG .
HUMAN MOLECULAR GENETICS, 1993, 2 (11) :1847-1851
[8]   HUMAN NAIVE CD4 T-CELLS PRODUCE INTERLEUKIN-4 AT PRIMING AND ACQUIRE A TH2 PHENOTYPE UPON REPETITIVE STIMULATIONS IN NEUTRAL CONDITIONS [J].
DEMEURE, CE ;
YANG, LP ;
BYUN, DG ;
ISHIHARA, H ;
VEZZIO, N ;
DELESPESSE, G .
EUROPEAN JOURNAL OF IMMUNOLOGY, 1995, 25 (09) :2722-2725
[9]   Induction of T(H)1 and T(H)2 immunity in neonatal mice [J].
Forsthuber, T ;
Yip, HC ;
Lehmann, PV .
SCIENCE, 1996, 271 (5256) :1728-1730
[10]   STUDIES OF HUMAN CORD-BLOOD DENDRITIC CELLS - EVIDENCE FOR FUNCTIONAL IMMATURITY [J].
HUNT, DWC ;
HUPPERTZ, HI ;
JIANG, HJ ;
PETTY, RE .
BLOOD, 1994, 84 (12) :4333-4343