Flow injection chemiluminescence determination of thiamine based on its enhancing effect on the luminol-hydrogen peroxide system

被引：39

作者：

Du, JX ^{[1
]}

Li, YH ^{[1
]}

Lu, JR ^{[1
]}

机构：

[1] Shaanxi Normal Univ, Dept Chem, Sch Chem & Mat Sci, Xian 710062, Peoples R China

来源：

TALANTA | 2002年 / 57卷 / 04期

关键词：

thiamine; flow injection; chemiluminescence; luminol;

D O I：

10.1016/S0039-9140(02)00079-6

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A new flow injection chemiluminescence (CL) method is proposed for the determination of thiamine, based upon its enhancing effect on the CL reaction of luminol with hydrogen peroxide in alkaline solution. The method allows the determination of thiamine within 0.05-8 mug ml(-1) range with a detection limit (3sigma) of 0.01 mug ml(-1). The relative standard deviation is 1.4% (n = 11, 0.5 mug ml(-1) thiamine) and the sample throughput is about 90 samples h(-1). The method was successfully applied to the determination of thiamine in pharmaceutical preparations. (C) 2002 Elsevier Science: B.V. All rights reserved.

引用

页码：661 / 665

页数：5

共 23 条

[1] Anodic adsorptive voltammetric determination of the vitamin B1 (thiamine) [J].

Aboul-Kasim, E .

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2000, 22 (06) :1047-1054

[2] CHEMILUMINESCENCE DETECTION OF SODIUM-NITROPRUSSIDE USING FLOW-INJECTION ANALYSIS [J].

ALWARTHAN, AA .

TALANTA, 1994, 41 (10) :1683-1688

[3] Chemiluminescent determination of pyridoxine hydrochloride in pharmaceutical samples using flow injection [J].

Alwarthan, AA ;

Aly, FA .

TALANTA, 1998, 45 (06) :1131-1138

[4] Sensitive assay for clavulanic acid and sulbactam in pharmaceuticals and blood serum using a how-injection chemiluminometric method [J].

Aly, FA ;

Alarfaj, NA ;

Alwarthan, AA .

ANALYTICA CHIMICA ACTA, 2000, 414 (1-2) :15-23

[5] Flow injection on-line photochemical reaction coupled to spectrofluorimetry for the determination of thiamine in pharmaceuticals and serum [J].

Chen, HW ;

Zhu, JP ;

Cao, XX ;

Fang, QJ .

ANALYST, 1998, 123 (05) :1017-1021

[6] Novel spectrofluorimetric method for the determination of thiamine with iron(III) tetrasulfonatophthalocyanine as a catalyst [J].

Chen, QY ;

Li, DH ;

Yang, HH ;

Zhu, QZ ;

Zheng, H ;

Xu, JG .

ANALYST, 1999, 124 (05) :771-775

[7]

Chen XM, 1999, CHINESE J ANAL CHEM, V27, P1435

[8] Flow injection turbidimetric determination of thiamine in pharmaceutical formulations using silicotungstic acid as precipitant reagent [J].

Costa-Neto, CO ;

Pereira, AV ;

Aniceto, C ;

Fatibello, O .

TALANTA, 1999, 48 (03) :659-667

[9]

DINIGA E, 1998, CHEM ANAL, V43, P437

[10]

ERDEY L., 1962, TALANTA, V9, P653, DOI 10.1016/0039-9140(62)80149-0

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