Is the progress zone model a victim of progress?

被引：18

作者：

Saunders, JW

机构：

[1] Box 3381, Waquoit

来源：

CELL | 2002年 / 110卷 / 05期

关键词：

D O I：

10.1016/S0092-8674(02)00936-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The prevailing view has long been that mesenchymal cells at the apex of the vertebrate limb bud proliferate in a progress zone (PZ) under the influence of the apical ectodermal ridge (AER). According to the PZ model, proximodistal cell fates are specified according to the time spent in the PZ. New results, considered along with some earlier findings, fail to support this model.

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收藏

页码：541 / 543

页数：3

相关论文

共 9 条

[1] Manifestation of the limb prepattern: Limb development in the absence of sonic hedgehog function [J].

Chiang, C ;

Litingtung, Y ;

Harris, MP ;

Simandl, BK ;

Li, Y ;

Beachy, PA ;

Fallon, JF .

DEVELOPMENTAL BIOLOGY, 2001, 236 (02) :421-435

[2] The roles of FGFs in the early development of vertebrate limbs [J].

Martin, GR .

GENES & DEVELOPMENT, 1998, 12 (11) :1571-1586

[3]

PIERCE RV, 1998, J EXP ZOOL, V282, P687

[4] ECTODERMAL-MESODERMAL INTERACTIONS IN GROWTH OF LIMB BUDS IN CHICK-EMBRYO - CONSTANCY AND TEMPORAL LIMITS OF ECTODERMAL INDUCTION [J].

RUBIN, L ;

SAUNDERS, JW .

DEVELOPMENTAL BIOLOGY, 1972, 28 (01) :94-&

[5] THE PROXIMO-DISTAL SEQUENCE OF ORIGIN OF THE PARTS OF THE CHICK WING AND THE ROLE OF THE ECTODERM [J].

SAUNDERS, JW .

JOURNAL OF EXPERIMENTAL ZOOLOGY, 1948, 108 (03) :363-403

[6]

Saunders JW J., 1968, EPITHELIAL MESENCHYM, P78

[7] POSITIONAL INFORMATION IN CHICK LIMB MORPHOGENESIS [J].

SUMMERBELL, D ;

LEWIS, JH ;

WOLPERT, L .

NATURE, 1973, 244 (5417) :492-496

[8] Functions of FGF signalling from the apical ectodermal ridge in limb development [J].

Sun, X ;

Mariani, FV ;

Martin, GR .

NATURE, 2002, 418 (6897) :501-508

[9]

TUTTLE A, 2002, NATURE, V418, P539