Coaggregation interactions between oral and endodontic Enterococcus faecalis and bacterial species isolated from persistent apical periodontitis

被引:47
作者
Johnson, Erika M. [1 ]
Flannagan, Susan E. [1 ]
Sedgley, Christine M. [1 ]
机构
[1] Univ Michigan, Dept Cariol Restorat Sci & Endodont, Sch Dent, Ann Arbor, MI 48109 USA
关键词
apical periodontitis; bacteria; coaggregation; endodontic; Enterococcus faecalis;
D O I
10.1016/j.joen.2006.03.023
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Interactions between Enterococcus faecalis and other species found in root canal infections might be important for the development and persistence of periapical disease. The aim of this study was to investigate the coaggregation interactions between E. faecalis clinical isolates and species previously shown to survive and induce apical periodontitis in monkeys: Peptostreptococcus anaerobius, Prevotella oralis, Fusobacterium nucleatum, and Streptococcus anginosus. Intergeneric coaggregation assays were conducted in duplicate with observations scored immediately at 0 h, 1 h and 24 h after mixing of combinations of strains. All E. faecalis strains (n = 53) coaggregated with F. nucleatum; E. faecalis did not coaggregate with P. anaerobius or S. anginosus. One strain, E. faecalis El, coaggregated with P. oralis, with aggregates visible at 1 h. Coaggregation interactions between E. faecalis and F. nucleatum observed in this study suggest a potential role for this combination in endodontic infections.
引用
收藏
页码:946 / 950
页数:5
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