New factors in the regulation of adipose differentiation and metabolism

被引：62

作者：

Holst, D ^{[1
]}

Grimaldi, PA ^{[1
]}

机构：

[1] Univ Nice, UFR Sci, Ctr Biochim, Inst Signaling Dev Biol & Canc, F-06108 Nice, France

来源：

CURRENT OPINION IN LIPIDOLOGY | 2002年 / 13卷 / 03期

关键词：

D O I：

10.1097/00041433-200206000-00002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Obesity and lipoatrophy are major risks for insulin resistance, type 2 diabetes and cardiovascular diseases. The molecular links between adipocyte dysfunction and metabolic disorders were elusive until the discovery that adipose tissue operates as an endocrine organ and releases factors targeting a wide range of organs. This article attempts to review the more recent advances from research on the transcriptional control of adipogenesis and on new adipocyte-secreted proteins that have been proposed as molecular links between adipose tissue and insulin resistance. Curr Opin Lipidol 13:241-245. (C) 2002 Lippincott Williams Wilkins.

引用

页码：241 / 245

页数：5

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