The state of the STATs: Recent developments in the study of signal transduction to the nucleus

被引：169

作者：

Horvath, CM

Darnell, JE

机构：

[1] Laboratory of Molecular Cell Biology, Rockefeller University, New York, NY 10021

来源：

CURRENT OPINION IN CELL BIOLOGY | 1997年 / 9卷 / 02期

关键词：

D O I：

10.1016/S0955-0674(97)80067-1

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The STATs (signal transducers and activators of transcription) are latent cytoplasmic proteins that, upon activation by cell surface bound polypeptide ligands, move to the nucleus to direct transcription. A variety of protein-protein interactions that affect the function of STATs has been recently recognized. It has become clear that the STATs are functional mosaics, or mixtures of signal transduction and transcription modules.

引用

页码：233 / 239

页数：7

共 73 条

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