Yeast go the whole HOG for the hyperosmotic response

被引：223

作者：

O'Rourke, SM ^{[1
]}

Herskowitz, I

O'Shea, EK

机构：

[1] Univ Calif San Francisco, Howard Hughes Med Inst, San Francisco, CA 94143 USA

[2] Univ Calif San Francisco, Dept Biochem & Biophys, San Francisco, CA 94143 USA

来源：

TRENDS IN GENETICS | 2002年 / 18卷 / 08期

关键词：

D O I：

10.1016/S0168-9525(02)02723-3

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

An evolutionarily conserved mitogen-activated protein kinase pathway-the high osmolarity glycerol (HOG) pathway-mediates the hyperosmotic response in Saccharomyces cerevisiae. A variety of powerful approaches has generated a comprehensive picture of how cells respond to this stress condition. Several presumptive osmosensors on the cell surface recruit and activate downstream signaling components, which regulate the activity of transcription factors to control gene expression.

引用

页码：405 / 412

页数：8

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