Use of deoxyribose by intestinal and extraintestinal pathogenic Escherichia coli strains:: a metabolic adaptation involved in competitiveness

被引:21
作者
Bernier-Fébreau, C
du Merle, L
Turlin, E
Labas, V
Ordonez, J
Gilles, AM
Le Bouguénec, C
机构
[1] Inst Pasteur, Unite Pathogenis Bacterienne Muqueuses, F-75724 Paris 15, France
[2] Inst Pasteur, Unite Genet Genomes Bacteriens, Paris, France
[3] Inst Pasteur, Lab Chim Structurale Macromol, Paris, France
[4] ESPCI, Lab Neurobiol & Divers Cellulaire, F-75005 Paris, France
关键词
D O I
10.1128/IAI.72.10.6151-6156.2004
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We showed that the deoK operon, which confers the ability to use deoxyribose as a carbon source, is more common among pathogenic than commensal Escherichia coli strains. The expression of the deoK operon increases the competitiveness of clinical isolates, suggesting that this biochemical characteristic plays a role in host infectivity.
引用
收藏
页码:6151 / 6156
页数:6
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