When biotoxins are tools of terror - Early recognition of intentional poisoning can attenuate effects

被引:9
作者
Blazes, DL [1 ]
Lawler, JV [1 ]
Lazarus, AA [1 ]
机构
[1] Natl Naval Med Res Inst, Infect Dis Serv, Bethesda, MD 20889 USA
关键词
D O I
10.3810/pgm.2002.08.1278
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Capable of causing disease as well as being therapeutic, toxins have been both a curse and a blessing for millennia. Now, the threat of rogue countries or terrorist organizations using toxins as weapons of war is very real. In this article, Drs Blazes, Lawler, and Lazarus review the clinical and epidemiologic features of the toxin mediated diseases most likely to occur as a result of a biological warfare event.
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收藏
页码:89 / +
页数:6
相关论文
共 19 条
[1]  
[Anonymous], 1998, Botulism in the United States, 1899-1996. Handbook for epidemiologists, clinicians
[2]  
[Anonymous], 1972, CONVENTION PROHIBITI
[3]   Botulinum toxin as a biological weapon - Medical and public health management [J].
Arnon, SS ;
Schechter, R ;
Inglesby, TV ;
Henderson, DA ;
Bartlett, JG ;
Ascher, MS ;
Eitzen, E ;
Fine, AD ;
Hauer, J ;
Layton, M ;
Lillibridge, S ;
Osterholm, MT ;
O'Toole, T ;
Parker, G ;
Perl, TM ;
Russell, PK ;
Swerdlow, DL ;
Tonat, K .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 285 (08) :1059-1070
[4]   DETECTION OF TRACE LEVELS OF TRICHOTHECENE MYCOTOXINS IN HUMAN-URINE BY GAS-CHROMATOGRAPHY MASS-SPECTROMETRY [J].
BLACK, RM ;
CLARKE, RJ ;
READ, RW .
JOURNAL OF CHROMATOGRAPHY, 1986, 367 (01) :103-115
[5]  
CIEGLER A, 1975, LLOYDIA, V38, P21
[6]   Clinical recognition and management of patients exposed to biological warfare agents [J].
Franz, DR ;
Jahrling, PB ;
Friedlander, AM ;
McClain, DJ ;
Hoover, DL ;
Bryne, WR ;
Pavlin, JA ;
Christopher, CW ;
Eitzen, EM .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1997, 278 (05) :399-411
[7]  
FRANZ DR, 1997, MED ASPECTS CHEM B 1, V3, P603
[8]   HIGH-AFFINITY BINDING OF STAPHYLOCOCCAL ENTEROTOXIN-A AND ENTEROTOXIN-B TO HLA-DR [J].
FRASER, JD .
NATURE, 1989, 339 (6221) :221-223
[9]   ASSESSMENT OF EFFICACY OF ACTIVATED-CHARCOAL FOR TREATMENT OF ACUTE T-2 TOXIN POISONING [J].
FRICKE, RF ;
JORGE, J .
JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY, 1990, 28 (04) :421-431
[10]   Indirect electrochemical detection of type-B trichothecene mycotoxins [J].
Hsueh, CC ;
Liu, Y ;
Freund, MS .
ANALYTICAL CHEMISTRY, 1999, 71 (18) :4075-4080