A DNA damage checkpoint in Escherichia coli

被引：5

作者：

Cairns, J ^{[1
]}

机构：

[1] Radcliffe Infirm, Clin Trial Serv Unit, Oxford OX2 6HE, England

来源：

DNA REPAIR | 2002年 / 1卷 / 08期

关键词：

Escherichia coli; DNA damage; checkpoint; apoptosis;

D O I：

10.1016/S1568-7864(02)00076-9

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

An early attempt to find out if the DNA double helix is actively unwound before being replicated was not conclusive, but it did disclose the existence of a unique moment in the life cycle of Escherichia coli when the cell registers whether or not its DNA is intact. If not, the cell embarks on rapid breakdown of its DNA, like "apoptosis" in eukaryotic cells. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：699 / 701

页数：3

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