The potential for elemental analysis in biotechnology

被引：58

作者：

Baranov, VI ^{[1
]}

Quinn, ZA ^{[1
]}

Bandura, DR ^{[1
]}

Tanner, SD ^{[1
]}

机构：

[1] MDS SCIEX, Concord, ON L4K 4V8, Canada

来源：

JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY | 2002年 / 17卷 / 09期

关键词：

D O I：

10.1039/b201494g

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The ICP-MS brings particular attributes to the method that distinguishes it from organic mass spectrometry: relative insensitivity to concomitant organic or metallic species, equivalent sensitivity to all similarly-tagged complexes, inherent ability to provide absolute quantitation and linearity of response. All these positive features fit the requirements of modern-day biotechnology. In this work, the potential of ICP-MS is discussed in the context of several urgent problems of biotechnology including: the determination of the state of phosphorylation of proteins, quality control of biologically active materials and control of efficiency of cell line transfections.

引用

页码：1148 / 1152

页数：5

共 39 条

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