Convenient synthesis of L-proline benzyl ester

被引：7

作者：

Córdova, A ^{[1
]}

Reed, NN ^{[1
]}

Ashley, JA ^{[1
]}

Janda, KD ^{[1
]}

机构：

[1] Scripps Res Inst, Skaggs Inst Chem Biol, Dept Chem & Mol Biol, La Jolla, CA 92037 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1999年 / 9卷 / 21期

关键词：

D O I：

10.1016/S0960-894X(99)00546-6

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Mesylates or tosylates of delta-hydroxy-L-norvaline esters spontaneously afford L-proline esters upon exposure to aqueous buffer in near quantitative yield. This novel reaction has led to the development of a simple route to optically active proline esters. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：3119 / 3122

页数：4

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