Searching for the middle ground: mechanisms of chromosome alignment during mitosis

被引：73

作者：

Kapoor, TM

Compton, DA

机构：

[1] Rockefeller Univ, Lab Chem & Cell BIol, New York, NY 10021 USA

[2] Dartmouth Coll, Sch Med, Dept Biochem, Hanover, NH 03755 USA

来源：

JOURNAL OF CELL BIOLOGY | 2002年 / 157卷 / 04期

关键词：

chromosome; congression; traction fiber; poleward flux; kinesin;

D O I：

10.1083/jcb.200202073

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The contributions of key molecules predicted to align chromosomes at the center of the mitotic spindle have been recently examined. New results dictate that models for how chromosomes align during the early stages of mitosis must be revised to integrate properties of microtubule-based motor proteins as well as microtubule dynamics.

引用

收藏

页码：551 / 556

页数：6

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