Bioactivity of moschamindole from Centaurea moschata

被引：85

作者：

Kumarasamy, Y

Fergusson, ME

Nahar, L

Sarker, SD ^{[1
]}

机构：

[1] Robert Gordon Univ, Sch Pharm, Aberdeen AB10 1FR, Scotland

[2] Univ Aberdeen, Dept Chem, Japp Lab, Aberdeen, Scotland

来源：

PHARMACEUTICAL BIOLOGY | 2002年 / 40卷 / 04期

关键词：

Centaurea moschata; moschamindole; indole; antioxidant activity; antibacterial activity; brine shrimp lethality bioassay; Artemia salina;

D O I：

10.1076/phbi.40.4.307.8467

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The antioxidant and antibacterial properties of moschamindole (1), an indole alkaloid isolated from the methanol extract of the seeds of Centaurea moschata, have been assessed. General toxicity of this compound has also been determined by the brine shrimp lethality bioassay.

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页码：307 / 310

页数：4

相关论文

共 13 条

[1]

BAILEY LH, 1997, MANUAL CULTIVATED PL, P1026

[2] Moschamindole [J].

Cox, PJ ;

Fergusson, M ;

Nahar, L ;

Sarker, SD .

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2001, 57 :O81-O82

[3] Antioxidant activity of plant extracts containing phenolic compounds [J].

Kähkönen, MP ;

Hopia, AI ;

Vuorela, HJ ;

Rauha, JP ;

Pihlaja, K ;

Kujala, TS ;

Heinonen, M .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1999, 47 (10) :3954-3962

[4]

Kaij-a-Kamb M, 1992, Pharm Acta Helv, V67, P178

[5] BRINE SHRIMP - A CONVENIENT GENERAL BIOASSAY FOR ACTIVE-PLANT CONSTITUENTS [J].

MEYER, BN ;

FERRIGNI, NR ;

PUTNAM, JE ;

JACOBSEN, LB ;

NICHOLS, DE ;

MCLAUGHLIN, JL .

PLANTA MEDICA, 1982, 45 (01) :31-34

[6] Moschamine, cis-moschamine, moschamindole and moschamindolol: Four novel indole alkaloids from Centaurea moschata [J].

Sarker, SD ;

Savchenko, T ;

Whiting, P ;

Sik, V ;

Dinan, LN .

NATURAL PRODUCT LETTERS, 1997, 9 (03) :189-199

[7] (20R)-15α-hydroxy-8β,9α,14α,17α-pregn-4-en-3-one 20-O-β-D-glucopyranoside:: A minor constituent of the seeds of Centaurea moschata [J].

Sarker, SD ;

Lafont, R ;

Girault, JP ;

Sik, V ;

Dinan, L .

PHARMACEUTICAL BIOLOGY, 1998, 36 (03) :202-206

[8] Moschatine:: An unusual steroidal glycoside from Centaurea moschata [J].

Sarker, SD ;

Dinan, L ;

Sik, V ;

Rees, HH .

PHYTOCHEMISTRY, 1998, 48 (06) :1039-1043

[9] Occurrence of ecdysteroids in the genus Centaurea (Compositae): 20-hydroxyecdysone from Centaurea moschata [J].

Sarker, SD ;

Savchenko, T ;

Whiting, P ;

Sik, V ;

Lafont, R ;

Dinan, L .

BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 1997, 25 (04) :367-368

[10] Indole alkaloids from the seeds of Centaurea cyanus (Asteraceae) [J].

Sarker, SD ;

Laird, A ;

Nahar, L ;

Kumarasamy, Y ;

Jaspars, M .

PHYTOCHEMISTRY, 2001, 57 (08) :1273-1276