Thyroid transcription factor-1 is a marker of lung and thyroid carcinomas

被引：187

作者：

Ordóñez, NG ^{[1
]}

机构：

[1] Univ Texas, MD Anderson Canc Ctr, Houston, TX 77030 USA

来源：

ADVANCES IN ANATOMIC PATHOLOGY | 2000年 / 7卷 / 02期

关键词：

transcription factors; TTF-1; lung neoplasms; thyroid neoplasms; immunohistochemistry;

D O I：

10.1097/00125480-200007020-00007

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Thyroid transcription factor-1 (TTF-1) is a tissue specific transcription Factor expressed in epithelial cells of the thyroid and lung, as well as in certain areas of the brain. Recent investigations have shown that TTF-1 is also commonly present in a wide variety of thyroid and lung tumors. Because of its restrictive expression, TTF-1 is a useful immunohistochemical marker in the diagnosis of tumors of thyroid or lung origin.

引用

页码：123 / 127

页数：5

共 45 条

[1] AGOFF SN, IN PRESS MOD PATHOL
[2] Anwar F, 1999, LAB INVEST, V79, p181A
[3] Bejarano PA, 1999, LAB INVEST, V79, p66A
[4] Bejarano PA, 1996, MODERN PATHOL, V9, P445
[5] Thyroid transcription factor-1
Bingle, CD
[J]. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 1997, 29 (12) : 1471 - 1473
[6] Determination of lung as the primary site of cerebral metastatic adenocarcinomas using monoclonal antibody to thyroid transcription factor-1
Bohinski, RJ
Bejarano, PA
Balko, G
Warnick, RE
Whitsett, JA
[J]. JOURNAL OF NEURO-ONCOLOGY, 1998, 40 (03) : 227 - 231
[7] THE LUNG-SPECIFIC SURFACTANT PROTEIN-B GENE PROMOTER IS A TARGET FOR THYROID TRANSCRIPTION FACTOR-1 AND HEPATOCYTE NUCLEAR FACTOR-3, INDICATING COMMON FACTORS FOR ORGAN-SPECIFIC GENE-EXPRESSION ALONG THE FOREGUT AXIS
BOHINSKI, RJ
DILAURO, R
WHITSETT, JA
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1994, 14 (09) : 5671 - 5681
[8] LUNG CELL-SPECIFIC EXPRESSION OF THE MURINE SURFACTANT PROTEIN-A (SP-A) GENE IS MEDIATED BY INTERACTIONS BETWEEN THE SP-A PROMOTER AND THYROID TRANSCRIPTION FACTOR-I
BRUNO, MD
BOHINSKI, RJ
HUELSMAN, KM
WHITSETT, JA
KORFHAGEN, TR
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (12) : 6531 - 6536
[9] Alveolar adenoma: A histochemical, immunohistochemical, and ultrastructural analysis of 17 cases
Burke, LM
Rush, WI
Khoor, A
Mackay, B
Oliveira, P
Whitsett, JA
Singh, G
Turnicky, R
Fleming, MV
Koss, MN
Travis, WD
[J]. HUMAN PATHOLOGY, 1999, 30 (02) : 158 - 167
[10] Byrd-Gloster AL, 1999, LAB INVEST, V79, p182A

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