Quantitative analysis of gait in Parkinson's disease: a pilot study on the effects of bilateral sub-thalamic stimulation

被引:41
作者
Ferrarin, M
Lopiano, L
Rizzone, M
Lanotte, M
Bergamasco, B
Recalcati, M
Pedotti, A
机构
[1] Politecn Milan, Fdn Don Carlo Gnocchi ONLUS, Ctr Bioingn, I-20133 Milan, Italy
[2] Univ Turin, Dipartimento Neurol, Turin, Italy
[3] Osped CTO, Div Neurochirurg, Turin, Italy
[4] Fdn Salvatore Maugeri, Pavia, Italy
[5] Politecn Milan, Dipartimento Bioingn, I-20133 Milan, Italy
关键词
gait analysis; Parkinson's disease; subthalamic nucleus stimulation; deep brain stimulation; motor rehabilitation;
D O I
10.1016/S0966-6362(01)00204-1
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Four patients with Parkinson's disease who had a Subthalamic Nucleus (STN) stimulator implanted and four age-matched controls underwent gait analysis using a three-dimensional system. STN stimulation substantially improved most of the key variables in the patients, without producing inefficient compensatory movements of the trunk. A reduction of ankle power production during push off was the most persistent abnormality seen when the patients were stimulated. We also found a reduction of trunk lateral bending and torsion when the patients were not stimulated when compared with controls. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:135 / 148
页数:14
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