Cytotoxic constituents from Butea superba Roxb.

被引：23

作者：

Ngamrojanavanich, Nattaya

Loontaisong, Aimon

Pengpreecha, Somchai

Cherdshewasart, Wichai

Pornpakakul, Surachai

Pudhom, Khanitha

Roengsumran, Sophon

Petsom, Amorn

机构：

[1] Chulalongkorn Univ, Fac Sci, Dept Chem, Res Ctr Bioorgan Chem, Bangkok 10330, Thailand

[2] Chulalongkorn Univ, Fac Sci, Program Biotechnol, Bangkok 10330, Thailand

[3] Chulalongkorn Univ, Fac Sci, Dept Biol, Bangkok 10330, Thailand

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2007年 / 109卷 / 02期

关键词：

Butea superba; isoflavones; carpin; cytotmicity;

D O I：

10.1016/j.jep.2006.07.034

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

A carpin (3-hydroxy-9-methoxypterocarpan) (Medicarpin) (1) and four isoflavones, 7-hydroxy-4'-methoxy-isoflavone (Formononetin) (2); 7,4'-dimethoxyisoflavone (3); 5,4'-dihydroxy-7-methoxy-isoflavone (Prunetin) (4) and 7-hydroxy-6,4'-dimethoxyisoflavone (5) were isolated from the tuber roots of Butea superba Roxb. Compounds 2 and 4 showed moderate cytotoxic activity on KB cell lines with IC50 (mu M) values of 37.3 +/- 2.5 and 71.1 +/- 0.8 and on BC cell lines with IC50 (RM) values of 32.7 +/- 1.5 and 47.3 +/- 0.3, respectively. (c) 2006 Elsevier Ireland Ltd. All rights reserved.

引用

页码：354 / 358

页数：5

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