Circulating Non-coding RNA as Biomarkers in Colorectal Cancer

被引:27
作者
Ferracin, Manuela [1 ]
Lupini, Laura [2 ]
Mangolini, Alessandra [2 ]
Negrini, Massimo [2 ]
机构
[1] Univ Bologna, Dept Expt Diagnost & Specialty Med DIMES, Bologna, Italy
[2] Univ Ferrara, Dept Morphol Surg & Expt Med, Ferrara, Italy
来源
NON-CODING RNAS IN COLORECTAL CANCER | 2016年 / 937卷
关键词
MicroRNA; Serum; Plasma; Diagnostics; Colorectal cancer; Biomarkers; CELL-FREE MICRORNAS; PROGNOSTIC BIOMARKER; POOR-PROGNOSIS; SERUM MIR-21; PLASMA; EXPRESSION; MARKER; RECURRENCE; MIR-92A; STAGE;
D O I
10.1007/978-3-319-42059-2_9
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
Recent studies suggested that colorectal cancer influences the types and quantity of nucleic acids - especially microRNAs - detected in the blood-stream. Concentration of circulating (cell-free) microRNAs, and possibly of other non-coding RNAs, could therefore serve as valuable colorectal cancer biomarker and could deliver insight into the disease process. This chapter addresses the recent discoveries on circulating microRNA and long non-coding RNA as diagnostic or prognostic biomarkers in colorectal cancer.
引用
收藏
页码:171 / 181
页数:11
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