The neuromythology of Parkinson's disease

被引:30
作者
Calne, DB
Mizuno, Y
机构
[1] UBC Hosp, Pacific Parkinsons Res Ctr, Vancouver, BC V6T 2B5, Canada
[2] Juntendo Univ, Sch Med, Dept Neurol, Tokyo, Japan
关键词
Lewy bodies; Parkinson's disease;
D O I
10.1016/j.parkreldis.2004.03.006
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Over the last century three central points have become the orthodox dogma accepted and taught by those who study Parkinson's Disease. These are: 1. Parkinson's Disease is one disease. 2. Lewy bodies in the substantia nigra are an acceptable hallmark of Parkinson's Disease. 3. Lewy bodies are responsible for the death of nigral neurons in Parkinson's Disease. Each of these tenets now present difficulties, and we are beginning to enter an era in which we must look critically at the current evidence to decide whether each dictum can be sustained. (C) 2004 Published by Elsevier Ltd.
引用
收藏
页码:319 / 322
页数:4
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