Anticonvulsant activity of Mimosa pudica decoction

被引：55

作者：

Bum, EN

Dawack, DL

Schmutz, M

Rakotonirina, A

Rakotonirina, SV

Portet, C

Jeker, A

Olpe, HR

Herding, P

机构：

[1] Univ Ngaoundere, Dept Sci Biol, Fac Sci, Ngaoundere, BP, Cameroon

[2] Novartis Pharma Ltd Res, CH-4002 Basel, Switzerland

[3] Univ Yaounde, Dept Biol & Physiol Anim, Fac Sci, Yaounde, Cameroon

来源：

FITOTERAPIA | 2004年 / 75卷 / 3-4期

关键词：

Mimosa pudica; anticonvulsant; sedative; seizures;

D O I：

10.1016/j.fitote.2004.01.012

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The decoction of Mimosa pudica leaves given intraperitoneally at dose of 1000-4000 mg/kg protected mice against pentylentetrazol and strychnine-induced seizures. M. pudica had no effect against picrotoxin-induced seizures It also antagonized N-methyl-D-aspartate-induced turning behavior. These properties could explain its use in African traditional medicine. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：309 / 314

页数：6

共 14 条

[1] Hyperglycemic effect of leaves of Mimosa pudica Linn [J].