Antiulcerogenic activity of Alhagi maurorum

Six main flavonoid glycosides were isolated, for the first time, from the ethanol extract of Alhagi maurorum Boiss (Leguminosae). They were identified as kaempferol, chrysoeriol, isorhamnetin, chrysoeriol-7-O-xylosoid, kaempferol-3-galactorhamnoside, and isorhamnetin 3-O-beta-D-apio-furanosyl (1-2) beta-D-galactopyranoside. Their identities were established by m.p., UV, EI-mass, Fab-mass, 600 MHz H-1 and C-13 NMR. The total extract (300 and 400 mg/kg) and two of the isolated compounds (chrysoeriol 7-O-xylosoid and kaempferol-3-galactorhamnoside, 100 mg/kg each) showed a very promising antiulcerogenic activity with curative ratios 66.31%, 69.57%, 75.49%, and 77.93%, respectively.