Delaying the mitochondrial decay of aging

被引：75

作者：

Ames, BN

机构：

[1] Childrens Hosp Oakland, Res Inst, Oakland, CA 94609 USA

[2] Univ Calif Berkeley, Berkeley, CA 94720 USA

来源：

STRATEGIES FOR ENGINEERED NEGLIGIBLE SENESCENCE: WHY GENUINE CONTROL OF AGING MAY BE FORESEEABLE | 2004年 / 1019卷

关键词：

acetyl carnitine; lipoic acid; reversing genetic disease; high-dose B-vitamin; vitamin; minerals; and aging; heme deficiency; zinc deficiency; biotin deficiency; vitamin B6; pantothenic acid; copper deficiency;

D O I：

10.1196/annals.1297.073

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Mitochondrial dysfunction may be a principal underlying event in aging, including the degenerative diseases of aging such as brain degeneration. Mitochondria provide energy for basic metabolic processes, and their decay with age impairs cellular metabolism and leads to cellular decline. Progress over the last decade in delaying the mitochondrial decay of aging is reviewed.

引用

页码：406 / 411

页数：6

共 35 条

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