Human caliciviruses as a cause of severe gastroenteritis in Peruvian children

被引：34

作者：

Parashar, UD

Li, JF

Cama, R

DeZalia, M

Monroe, SS

Taylor, DN

Figueroa, D

Gilman, RH

Glass, RI

机构：

[1] Ctr Dis Control & Prevent, Resp & Enter Viruses Branch, Atlanta, GA 30333 USA

[2] Sch Hopkins Sch Hyg & Publ Hlth, Dept Int Hlth, Baltimore, MD USA

[3] Childrens Hlth Inst, Lima, Peru

[4] AB PRISMA, Lima, Peru

来源：

JOURNAL OF INFECTIOUS DISEASES | 2004年 / 190卷 / 06期

关键词：

D O I：

10.1086/423324

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To define the role of human caliciviruses (HuCVs) in severe childhood gastroenteritis, fecal and paired serum samples from 233 Peruvian children hospitalized with gastroenteritis (case patients) and fecal samples from 248 control subjects were evaluated. Overall, 128 case patients (55%) demonstrated HuCV infection by either fecal (n=81 [35%]) or serological (n=96[41%]) testing. HuCVs were more prevalent in fecal samples from case patients than those from control subjects (35% vs. 13%; P<.001). HuCV infection was more prevalent among case patients without another pathogen than in those who had a coinfecting pathogen (77% [40/52] vs. 49% [88/181]; P<.001). HuCVs appear to be an important cause of gastroenteritis in Peruvian children.

引用

页码：1088 / 1092

页数：5

共 21 条

[1] Genetic classification of "Norwalk-like viruses" [J].

Ando, T ;

Noel, JS ;

Fankhauser, RL .

JOURNAL OF INFECTIOUS DISEASES, 2000, 181 :S336-S348

[2] Prevalence of group A rotavirus, human calicivirus, astrovirus, and adenovirus type 40 and 41 infections among children with acute gastroenteritis in Dijon, France [J].

Bon, F ;

Fascia, P ;

Dauvergne, M ;

Tenenbaum, D ;

Planson, H ;

Petion, AM ;

Pothier, P ;

Kohli, E .

JOURNAL OF CLINICAL MICROBIOLOGY, 1999, 37 (09) :3055-3058

[3] Enteropathogens and other factors associated with severe disease in children with acute watery diarrhea in Lima, Peru [J].

Cama, RI ;

Parashar, UD ;

Taylor, DN ;

Hickey, T ;

Figueroa, D ;

Ortega, YR ;

Romero, S ;

Perez, J ;

Sterling, CR ;

Gentsch, JR ;

Gilman, RH ;

Glass, RI .

JOURNAL OF INFECTIOUS DISEASES, 1999, 179 (05) :1139-1144

[4] Effects of nutritional status on diarrhea in Peruvian children [J].

Checkley, W ;

Gilman, RH ;

Black, RE ;

Lescano, AG ;

Cabrera, L ;

Taylor, DN ;

Moulton, LH .

JOURNAL OF PEDIATRICS, 2002, 140 (02) :210-218

[5] Epidemiologic and molecular trends of "Norwalk-like viruses" associated with outbreaks of gastroenteritis in the United States [J].

Fankhauser, RL ;

Monroe, SS ;

Noel, JS ;

Humphrey, CD ;

Bresee, JS ;

Parashar, UD ;

Ando, T ;

Glass, RI .

JOURNAL OF INFECTIOUS DISEASES, 2002, 186 (01) :1-7

[6]

Farkas T, 2000, J MED VIROL, V62, P217, DOI 10.1002/1096-9071(200010)62:2&lt

[7]

217::AID-JMV13&gt

[8]

3.0.CO

[9]

2-F

[10] PREVALENCE OF ANTIBODY TO THE NORWALK VIRUS IN VARIOUS COUNTRIES [J].

GREENBERG, HB ;

VALDESUSO, J ;

KAPIKIAN, AZ ;

CHANOCK, RM ;

WYATT, RG ;

SZMUNESS, W ;

LARRICK, J ;

KAPLAN, J ;

GILMAN, RH ;

SACK, DA .

INFECTION AND IMMUNITY, 1979, 26 (01) :270-273

← 1 2 3 →