Origin, maturation and antigen presenting function of dendritic cells

被引：1119

作者：

Cella, M ^{[1
]}

Sallusto, F ^{[1
]}

Lanzavecchia, A ^{[1
]}

机构：

[1] BASEL INST IMMUNOL,CH-4005 BASEL,SWITZERLAND

来源：

CURRENT OPINION IN IMMUNOLOGY | 1997年 / 9卷 / 01期

关键词：

D O I：

10.1016/S0952-7915(97)80153-7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Dendritic cells are cells specialized for antigen capture, migration and T cell stimulation. Recent advances have been made in understanding their origin, their heterogeneity, the mechanism of antigen uptake, and the signals that induce their migration and maturation into immunostimulatory antigen-presenting cells. Dendritic cells represent the natural adjuvants for T cell responses and their therapeutic exploitation in the near future is foreseen.

引用

页码：10 / 16

页数：7

共 75 条

[1] THYMIC DENDRITIC CELLS AND T-CELLS DEVELOP SIMULTANEOUSLY IN THE THYMUS FROM A COMMON PRECURSOR POPULATION
ARDAVIN, C
WU, L
LI, CL
SHORTMAN, K
[J]. NATURE, 1993, 362 (6422) : 761 - 763
[2] New insights into the mobilization and phagocytic activity of dendritic cells
Austyn, JM
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 183 (04) : 1287 - 1292
[3] Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood
Bender, A
Sapp, M
Schuler, G
Steinman, RM
Bhardwaj, N
[J]. JOURNAL OF IMMUNOLOGICAL METHODS, 1996, 196 (02) : 121 - 135
[4] ANTIGEN PRESENTATION TO CYTOTOXIC T-LYMPHOCYTES IN-VIVO
BEVAN, MJ
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1995, 182 (03) : 639 - 641
[5] HUMAN EPIDERMAL LANGERHANS CELLS EXPRESS THE HIGH-AFFINITY RECEPTOR FOR IMMUNOGLOBULIN-E (FC-EPSILON-RI)
BIEBER, T
DELASALLE, H
WOLLENBERG, A
HAKIMI, J
CHIZZONITE, R
RING, J
HANAU, D
DELASALLE, C
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1992, 175 (05) : 1285 - 1290
[6] Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo
Boczkowski, D
Nair, SK
Snyder, D
Gilboa, E
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 184 (02) : 465 - 472
[7] ACTIVATION OF HUMAN DENDRITIC CELLS THROUGH CD40 CROSS-LINKING
CAUX, C
MASSACRIER, C
VANBERVLIET, B
DUBOIS, B
VANKOOTEN, C
DURAND, I
BANCHEREAU, J
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1994, 180 (04) : 1263 - 1272
[8] INTERLEUKIN-10 INHIBITS T-CELL ALLOREACTION INDUCED BY HUMAN DENDRITIC CELLS
CAUX, C
MASSACRIER, C
VANBERVLIET, B
BARTHELEMY, C
LIU, YJ
BANCHEREAU, J
[J]. INTERNATIONAL IMMUNOLOGY, 1994, 6 (08) : 1177 - 1185
[9] CD34(+) hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alpha
Caux, C
Vanbervliet, B
Massacrier, C
DezutterDambuyant, C
deSaintVis, B
Jacquet, C
Yoneda, K
Imamura, S
Schmitt, D
Banchereau, J
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 184 (02) : 695 - 706
[10] GM-CSF AND TNF-ALPHA COOPERATE IN THE GENERATION OF DENDRITIC LANGERHANS CELLS
CAUX, C
DEZUTTERDAMBUYANT, C
SCHMITT, D
BANCHEREAU, J
[J]. NATURE, 1992, 360 (6401) : 258 - 261

← 1 2 3 4 5 6 7 8 →