In vitro studies of two triazole antifungal agents (Voriconazole [UK-109,496] and fluconazole) against Candida species

被引：105

作者：

Barry, AL

Brown, SD

机构：

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1996年 / 40卷 / 08期

关键词：

D O I：

10.1128/AAC.40.8.1948

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A new triazole derivative (voriconazole or UK-109,496) and fluconazole were tested against 249 isolates of Candida spp, representing six species. Voriconazole was 10 to 100 times more potent than fluconazole. Strains with decreased susceptibility to fluconazole were inhibited by relatively low concentrations of voriconazole.

引用

页码：1948 / 1949

页数：2