Value of the chlorhexidine decontamination method for recovery of nontuberculous mycobacteria from sputum samples of patients with cystic fibrosis

被引：48

作者：

Ferroni, A

Vu-Thien, H

Lanotte, P

Le Bourgeois, M

Sermet-Gaudelus, I

Fauroux, B

Marchand, S

Varaigne, F

Berche, P

Gaillard, JL

Offredo, C

机构：

[1] Hop Necker Enfants Malad, Microbiol Serv, Assistance Publ Hop Paris, Microbiol Lab, F-75015 Paris, France

[2] Hop Trousseau, AP HP, Microbiol Lab, F-75571 Paris, France

[3] Hop Bretonneau, Microbiol Lab, Tours, France

[4] Hop Necker Enfants Malad, AP HP, Serv Pneumol Allergol Pediat, Paris, France

[5] Hop Necker Enfants Malad, AP HP, Serv Pediat Gen, Paris, France

[6] Hop Trousseau, AP HP, Serv Pneumol Pediat, F-75571 Paris, France

[7] Hop Pediat Gatien Clocheville, Serv Pediat, Tours, France

[8] Hop Bretonneau, Serv Pneumol, Tours, France

[9] Hop Ray Poincare, AP HP, Microbiol Lab, Garches, France

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2006年 / 44卷 / 06期

关键词：

D O I：

10.1128/JCM.00285-06

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The chlorhexidine method was compared to the N-acetyl-L-cysteine-NaOH-oxalic acid decontamination method currently recommended for the recovery of nontuberculous mycobacteria (NTM) from patients with cystic fibrosis. Sputum samples (n = 827) treated with chlorhexidine yielded twice as many NTM-positive cultures as those treated by the reference method (54 [6.50%] versus 27 (3.25%]; P < 0.0001) despite a higher contamination rate (20% versus 14.2%; P = 0.0017).

引用

页码：2237 / 2239

页数：3

共 18 条

[1] Improved decontamination method for recovering mycobacteria from patients with cystic fibrosis [J].