An unusual cyclization in a bis(cysteinyl-S) diiron complex related to the active site of Fe-only hydrogenases

被引：25

作者：

He, CJ

Wang, M

Zhang, XF

Wang, Z

Chen, CN

Liu, JH

Åkermark, B

Sun, LC

机构：

[1] Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116012, Peoples R China

[2] Fujian Inst Res Struct Matter, State Key Lab Struct Chem, Fujian 350002, Peoples R China

[3] Univ Stockholm, Arrhenius Lab, Dept Organ Chem, S-10691 Stockholm, Sweden

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 27期

关键词：

S ligands; cyclization; enzyme models; iron hydrogenases; structure elucidation;

D O I：

10.1002/anie.200453961

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Classical organometallic chemistry was used to prepare the dinuclear iron complex 1 with two protected cysteinyl-S ligands. Oxidative addition of the thiol to [Fe3(CO)12] gave complex 1, which undergoes an unusual intramolecular nucleophilic cyclization with inversion of the configuration to form the chiral carbon-bridged diiron complex 2.

引用

页码：3571 / 3574

页数：4

共 24 条

[1] Organometallic iron: the key to biological hydrogen metabolism [J].