Heritable colorectal cancer syndromes: recognition and preventive management

被引：56

作者：

Boardman, LA ^{[1
]}

机构：

[1] Mayo Clin & Mayo Fdn, Div Gastroenterol & Hepatol, Dept Internal Med, Rochester, MN 55905 USA

来源：

GASTROENTEROLOGY CLINICS OF NORTH AMERICA | 2002年 / 31卷 / 04期

关键词：

D O I：

10.1016/S0889-8553(02)00049-3

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Nearly one fifth of all colorectal cancers (CRC) arise in the context of a family history of CRC. Hereditary nonpolyposis colorectal cancer, familial adenomatous polyposis, juvenile polyposis syndrome, and Peutz-Jeghers syndrome are the four main familial CRC syndromes that have been characterized both clinically and genetically. Current methods for recognizing that an individual might belong to a CRC kindred are discussed, and screening and treatment recommendations are outlined for these four syndromes.

引用

页码：1107 / +

页数：26

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